Tag Archives: Calcium Antagonists

Treatment Of Coronary Disease


When the blood flow through the coronary arteries is sufficiently restricted to cause angina, there are two basic ways of helping: either the needs of the heart can be reduced so that and inadequate blood supply becomes adequate, or the arteries themselves can be treated to increase the blood supply. The former method is achieved with medicines and the latter, usually, with surgery.

The medicines work by lowering the hearts needs. They do this by slowing the heart rate, reducing the blood pressure (hence the “resistance” into which the heart has to pump) and also the force with which the heart contracts. There are three groups of drugs which are effective in this way; they are called beta-blockers, nitrates and calcium antagonists. To a minor extent they may dilate narrowed coronary arteries where “spasm” has narrowed them over and above the thickening in the walls.